Vienna will support older MacOS releases for longer. Our development has been slow the past couple of years due to maintainers having big life changes. Things are about to pick up so keep an eye out!
I tried to find a site with more examples than the linked post, and I think https://guis.org/macos/icons/ is a pretty good overview for those who may be interested.
I'd like to, but can't find a practical way to do so.
I doubt there is any consumer level service that would do this- the "23andme for dogs" type services likely aren't setup for this. It would need to be a professional level biotech project, where one would prepare the sample themselves and send it off for sequencing where you get just raw data back.
I am an academic scientist with a lab, and know how to do this, but feel it would be inappropriate to use my work facilities for such a project.
And in any case, you may not really get any conclusive data back anyhow.
CBC Marketplace sent a _human_ DNA sample to various dog DNA testing places and from some of them got an actual dog breed answer back (instead of the expected "error, not dog DNA").
So if you send "wolf" to a dog DNA testing place, how accurate would that really be for "wolf" vs. "dog" when all they expect to find is "dog" (and "wolf" is very close to "dog" given overall ancestry)?
Knowing how these services work that is not surprising- most only use a microarray that can only identify the approximate relative abundance of specific small fragments of DNA, it does not read the DNA sequence directly. They then probably have a very primitive analysis that assumes you have dog dna, and returns the same breed as whatever reference sample it is closest to. They almost certainly would have no reference data on a highly endangered African wolf.
For human vs. dog I would definitely expect that all of them would be able to tell (given that _some_ of them definitely were able to tell).
For wolf vs. dog I'd not be so certain even for the reputable ones. But then again I'm not a geneticist, so I can't tell you how easy it is to tell their version of "is this C# or Java byte code" :grin:
They don’t get the DNA sequence with these cheap microarray based services. However a human or something just as directly related to a dog would give weird mostly nonsense outputs- even if they could not tell what species the sample is actually from, it would be clearly not a dog. They should detect and reject those samples, but I am not surprised some of the services didn’t bother to implement that, as it requires more work.
Can you buy the primers personally for a few selected regions of great variability, do the extraction and PCR, and pay for sending it off for sequencing personally? You don't really need whole genome coverage and I'm sure if you asked if you could use a few ml of lysis buffer nobody would care. The scariest part for me would be sticking a buccal swab in your wolfdog's mouth...
Yes, that could possibly work with some carefully selected Sanger sequencing- I'd have to start with finding region(s) that had something I expected to be able to meaningfully interpret, which itself wouldn't be trivial, especially if the dog ends up being some type of wolfdog hybrid or just generally a less domesticated 'archaic dog.' Thanks for the suggestion- I'll look into it.
If it is an Ethiopian wolf, then it is one of the rarest animals on earth, and I suspect that many organizations would be more than willing to stump up for the testing.
I’d start by dropping into a local zoo, with photos.
When you install WireGuard client, there's "On Demand" option there that you can enable. That option has two additional settings - it can turn WireGuard only for a particular list of SSIDs, or it can _not_ turn it on for a particular list of SSIDs. So you just add the SSID of your home WiFi to the list for which WireGuard will not be turned on. On macOS client there is an identical option. This works really well.
You know just after I wrote that comment, I stuck "crispy duck" into google and that place came up.
You're right I don't think they have exactly what I describe, but it did look good and with a recommendation as well it's probably worth a punt. Thanks :)
Honest question - I've been using Ivory for the past week but it doesn't seem to do anything that Metatext or the Mastodon app didn't already do. What's so fantastic about Ivory? I feel like I'm missing something because everyone speaks so highly of Ivory.
I do like Metatext but development is paused (repo is archived) - and notifications appear to have stopped working. I'll probably end up back on Toot! at some point.
(Tried building my own version from the repo but it breaks for some reason and I'm not an iOS dev who can figure out why.)
I'll have a go at building it and if I'm successful I'll let you know. I honestly thought a proper fork would have started by now but that is not the case.
That’s not it in Australia - we don’t use asphalt roofing. Normal roofs are tile, steel or (more rarely) zinc here.
I think the US is fairly unique in that regard. I’m so used to our houses here that the idea of using shingles made of asphalt just seems bizarre to me.
It isn't working for me, and strangely enough the signal Twitter account has no mention of the outage. Their status page also claims everything is operational.
At least there is an in app notification about technical difficulties but it would be nice to see from an official source if it is an isolated incident or not.
