Broad Institute of MIT and Harvard | Cambridge, MA | Software Engineers | REMOTE or HYBRID
The Broad Institute of MIT and Harvard is a leading, world-renowned research organization that pioneers new ways to treat and prevent disease. Our dynamic team, comprising a diverse community of researchers and scientists, is at the forefront of genomic medicine and data analysis, always pushing the boundaries of what is possible in biomedical research. You will contribute to projects of global significance and have the opportunity to showcase your work as many of our projects are open-source. We offer a comprehensive benefits package and flexible remote work setting, fostering an inclusive environment. If you're excited about working on groundbreaking projects and making a real-world impact, come join us!
Data Engineer: We need a skilled Data Engineer to design, build, and maintain data pipelines for storing/querying very large genomic datasets. You'll be instrumental in devising an ecosystem that supports a growing number of projects, annotations, and dataset types. You will create data models and processing graphs, writing scalable CI/CD data pipelines, and work with a friendly and committed team of researchers and engineers (https://docs.google.com/document/d/1m4qRbB1thhnsMFXxDLtQRGOA...). To apply, email Matt (msolomon@broadinstitute.org) with a resume.
Associate Software Engineer: We're looking for an Associate Software Engineer focused on frontend development. You'll be involved in developing the next generation of web applications for visualizing genetic association results. You'll work with leading researchers in disease areas like schizophrenia, bipolar disorder, and inflammatory bowel disease. Your contributions will play a critical role in our understanding of complex diseases (https://docs.google.com/document/d/1eqt-FtiNj1qwu9HpkImrZROc...). To apply, email Matt (msolomon@broadinstitute.org) with a resume.
Software Engineer: You'll be involved in developing the seqr platform which is used by an international consortium of collaborating clinicians, researchers, and industry partners, to significantly improve their ability to search through large genomic datasets and make discoveries and diagnoses. seqr is core to our efforts both in the Rare Genomes Project and the Broad Center for Mendelian Genomics, and has already enabled us to provide genetic diagnoses to more than 2,000 rare disease families. We are now looking for a full-stack software engineer that will help with the next phase of this project (https://docs.google.com/document/d/16Byq42oUSIIpDomIhy9XIyHs...). To apply, email Larry (lbabb@broadinstitute.org) with a resume.
I'm a Research Software Engineer with a PhD working in Harvard/MIT area for > 5 years. I skipped doing a postdoc and have been part several high-profile academic projects in genomics. Overall I've loved the experience and can be a great move for certain people.
A major pain point in RSE is building and sustaining larger software teams around a
a single, focused long-term project with ~6-8 RSEs working together. Even the most well-funded and successful academic labs have a limit to what how much RSE effort they can support.
We need new funding models where engineering-focused leaders can muster sufficient resources (autonomously) to build great software teams that maintain high quality software in the long run. Focused Research Organizations (FROs) seem like an interesting new idea (https://www.dayoneproject.org/ideas/focused-research-organiz...).
Broad Institute of MIT and Harvard | Cambridge, MA | Software Engineer | REMOTE or HYBRID (New England area)
gnomAD is a resource for sharing the world's largest collection of human genome/exome sequences and is used by nearly half a million clinicians and scientists each year from almost every country.
Looking for a mission-driven front end developer with proven skills in data visualization and/or designing interfaces for exploring large, complex datasets. Join us as we scale to over 1 millions human samples and develop novel variant analysis functionality in collaboration with the some of the top scientists in the human genetics.
Broad Institute of MIT and Harvard | Cambridge, MA | Frontend Software Engineer | REMOTE or HYBRID (New England area)
We are hiring a frontend developer to help lead the next phase of the gnomAD browser, a web application for displaying the world's largest collection of human genome/exome sequences. https://gnomad.broadinstitute.org. Looking for applicants who are excited about data visualization and designing complex interfaces for scientific research.
Broad Institute of MIT and Harvard | New England | Software Engineer | REMOTE/HYBRID
Our team is focused on building the tools necessary to visualize and interpret massive data sets of human genetic variation and functional genomic information. We have developed gnomAD (https://gnomad.broadinstitute.org), the world’s largest public reference dataset of human exomes and genomes. gnomAD has become one of the most widely used resources in the field, and is now the default reference database for virtually all clinical interpretation pipelines, as well as a standard analysis resource for a wide variety of genetic and biological studies. We estimate gnomAD has contributed to the clinical diagnosis of over 2 million patients with genetic disorders.
Your role will be to maintain the gnomAD browser, our open source web application for exploring gnomAD and related datasets, and develop new scientific functionality as we continue to grow to over 1 million human samples. You will work with a team of software engineers, computational biologists and clinical and research users to develop new features and visualizations that incorporate user feedback. Software engineering skills and an interest in user interface design and data visualization are key. Basic familiarity with genomics and DNA sequencing data is preferred, but not required. Most importantly, the ideal candidate will have enthusiasm for playing a critical role in a team-oriented project and learning new domains.
Minimum Requirements
• Bachelors or Masters degree in Computer Science or related field or equivalent experience.
• Experience with React, CSS, D3, GraphQL, Python.
• Experience building web-based applications with a focus on quality and incorporating user feedback.
• Highly collaborative attitude and ability to work well in a team setting.
• Excellent communication skills.
• Demonstrated attention to detail and analytical skills.
An ideal candidate could have any of the following:
• Experience with Docker, Kubernetes, and a major cloud provider (Compute, Object Storage, IAM, Functions-as-a-Service) is a plus.
• Experience with bioinformatics datasets and analyses is a big plus.
What we offer:
• The chance to work on a project of international significance with a clear impact on families affected by rare genetic disorders.
• The opportunity to share your work: many of our projects are open source, allowing you to showcase your contributions with the community.
• Flexible remote work setting.
Comprehensive benefits package.
Email Matt with resume and examples of previous work: msolomon@broadinstitute.org
Broad Institute of MIT and Harvard | Cambridge, MA | Associate Software Engineer | Onsite/Remote Hybrid
We are seeking an associate software engineer interested in contributing to an open-source data visualization library for analyzing the biological impact human genetic variation. You will contribute to projects like gnomAD (https://gnomad.broadinstitute.org), the world's largest catalogue of human genetic variation used by hundreds of thousands of researchers. We are also developing next-generation tools for enabling genetic analyses of large biobanks across richly phenotyped individuals (https://genebass.org). In this role you will gain experience developing data-intensive web applications with Typescript, React, Python, Terraform, Google Cloud Platform, and will make use of the scalable data analysis library Hail (https://hail.is). Key to our success is growing a strong team with a diverse membership who foster a culture of continual learning, and who support the growth and success of one another. Towards this end, we are committed to seeking applications from women and from underrepresented groups. We know that many excellent candidates choose not to apply despite their capabilities; please allow us to enthusiastically counter this tendency.
Please provide a CV and links to previous work or projects, ideally with contributions visible on Github.
Broad Institute of MIT and Harvard | Cambridge, MA | Senior Software Engineer | Onsite
We are seeking a full stack senior software engineer to join our team of scientists, engineers, computational biologists, physicians, and geneticists. You will contribute to projects like gnomAD (Genome Aggregation Database), the world's largest catalogue of human genetic variation [1, 2, 3] and new resources for visualizing genetic analyses of large biobanks across richly phenotyped individuals of diverse ancestry [4]. The applicant will develop data-intensive web applications with Typescript, React, and Python, has a good sense of design and is keen to learn about human genetics and biology. Key to our success is growing a strong team with a diverse membership who foster a culture of continual learning, and who support the growth and success of one another. Towards this end, we are committed to seeking applications from women and from underrepresented groups. We know that many excellent candidates choose not to apply despite their capabilities; please allow us to enthusiastically counter this tendency.
Broad Institute of MIT and Harvard | Cambridge, MA | DevOps Engineer | Onsite
We are seeking a DevOps Engineer to join our tightly knit team of scientists, software engineers, computational biologists, physicians, and geneticists. You will contribute to several high-profile genetics resources that have been used by tens of thousands of researchers and physicians who aim to understand the molecular basis for disease. Projects falling under your portfolio will include gnomAD (https://gnomad.broadinstitute.org), an unprecedented catalogue of human genetic variation at a massive scale; seqr (https://seqr.broadinstitute.org), genetic analysis software that has helped over one thousand families afflicted by debilitating rare genetic disorders receive a molecular diagnosis; ClinGen (https://clinicalgenome.org/), an expert curated public repository of clinical relevant genes and variants; and the COVID-19 Host Genetics Initiative (https://www.covid19hg.org/), a global collaborative of hundreds of investigators across over 40 countries with the goal of uncovering the genetic determinants behind susceptibility to COVID-19.
Responsibilities:
Work closely with other software engineers to develop robust architectural designs and continuous integration processes.
Handle identity access management, logging, alerts, and website traffic analytics. Analyze cloud compute costs, compile results, and propose cost-saving strategies. Develop and maintain automated workflows for processing large genetic datasets. Write build tools and scripts in Bash, Python, or JavaScript. Technologies relevant to this role: Docker, Kubernetes, Apache Kafka, Google Cloud Deployment Manager, Terraform, Apache Airflow, GCP Dataproc, and Hail (experience with all not required).
Key to our success is growing a strong team with a diverse membership who foster a culture of continual learning, and who support the growth and success of one another. Towards this end, we are committed to seeking applications from women and from underrepresented groups. We know that many excellent candidates choose not to apply despite their capabilities; please allow us to enthusiastically counter this tendency. If you are a DevOps engineer who is eager to grow professionally and to contribute to our team culture and to participate in high-impact, open science, then we encourage you to apply.
Broad Institute of MIT and Harvard | Cambridge, MA | Software Engineer | INTERNS, ONSITE, VISA
We are seeking a creative, self-motivated software engineer who is excited about building high-performance GraphQL APIs. You will work with data from hundreds of thousands of human genome sequences and other orthogonal biological datasets, with the goal of understanding how DNA sequence variation relates to human physiology, traits, and susceptibility to disease.
You will work closely with a tightly knit team of scientists, software engineers, computational biologists, medical doctors, and geneticists. Your code will be 100% open source, and you will play a critical part in making our results accessible to the larger scientific community.
Key to our success is growing a strong team with a diverse membership who foster a culture of continual learning, and who support the growth and success of one another. Towards this end, we are committed to seeking applications from women and from underrepresented groups. We know that many excellent candidates choose not to apply despite their capabilities; please allow us to enthusiastically counter this tendency. If you are a software engineer who is eager to grow professionally and to contribute to our team culture and to participate in high-impact, open science, then we encourage you to apply.
Broad Institute of MIT and Harvard | Cambridge/Boston, MA | Software Engineer | INTERNS, ONSITE, VISA
We're a small team of software engineers, computational biologists, clinicians, and geneticists building cutting-edge tools and methods for interpreting some of the largest genomic datasets in the world (~500,000,000 genetic variants in ~200,000 human genomes/exomes). We aim to determine how genetic variation alters our proteins, biochemical pathways, cells, tissues, physiology, and traits/susceptibility to disease.
This position involves developing a React component library for visualizing genomic data. We are looking for friendly people with demonstrated experience in web tech, an eye for design, and genuine excitement to learn new things. Experience building performant React web applications preferred. In your email, please link to an online portfolio/github repo, and bonus points if you've built a nontrivial data visualization app. Technologies we use: React, Redux, D3, SVG, Python, GraphQL, nodejs, Docker, Kubernetes, Google Cloud Platform.
In this role, you'll receive domain-specific training at a world-class research institute. We're supportive of candidates interested in transitioning to graduate school. Your work will be 100% open source and highly visible in the genetics/genomics community. Our tools are used by tens of thousands of researchers and physicians around the world who cure disease and make biological discoveries. Come help shape the future of human genetic data visualization and discovery!
email: msolomon@broadinstitute.org
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Broad Institute of MIT and Harvard | Cambridge, MA | Principal Software Engineer | ONSITE
We are looking for a senior-level full-stack but frontend-focused engineer, ideally with React experience, to provide technical leadership for a project supporting the largest research study in the world. We have a progressive, maturing engineering culture with people who care about the world and how we can positively impact it. We believe the treatment of human disease deserves world-class software engineering.
Experience in biology or medicine is not required. A background in Lisps or functional programming will be a good philosophical fit even though we use more mainstream technologies (JavaScript and Java) for most of our work. You can check out my LinkedIn profile [1] for more engineering philosophy.
The Broad Institute of MIT and Harvard is a leading, world-renowned research organization that pioneers new ways to treat and prevent disease. Our dynamic team, comprising a diverse community of researchers and scientists, is at the forefront of genomic medicine and data analysis, always pushing the boundaries of what is possible in biomedical research. You will contribute to projects of global significance and have the opportunity to showcase your work as many of our projects are open-source. We offer a comprehensive benefits package and flexible remote work setting, fostering an inclusive environment. If you're excited about working on groundbreaking projects and making a real-world impact, come join us!
Data Engineer: We need a skilled Data Engineer to design, build, and maintain data pipelines for storing/querying very large genomic datasets. You'll be instrumental in devising an ecosystem that supports a growing number of projects, annotations, and dataset types. You will create data models and processing graphs, writing scalable CI/CD data pipelines, and work with a friendly and committed team of researchers and engineers (https://docs.google.com/document/d/1m4qRbB1thhnsMFXxDLtQRGOA...). To apply, email Matt (msolomon@broadinstitute.org) with a resume.
Associate Software Engineer: We're looking for an Associate Software Engineer focused on frontend development. You'll be involved in developing the next generation of web applications for visualizing genetic association results. You'll work with leading researchers in disease areas like schizophrenia, bipolar disorder, and inflammatory bowel disease. Your contributions will play a critical role in our understanding of complex diseases (https://docs.google.com/document/d/1eqt-FtiNj1qwu9HpkImrZROc...). To apply, email Matt (msolomon@broadinstitute.org) with a resume.
Software Engineer: You'll be involved in developing the seqr platform which is used by an international consortium of collaborating clinicians, researchers, and industry partners, to significantly improve their ability to search through large genomic datasets and make discoveries and diagnoses. seqr is core to our efforts both in the Rare Genomes Project and the Broad Center for Mendelian Genomics, and has already enabled us to provide genetic diagnoses to more than 2,000 rare disease families. We are now looking for a full-stack software engineer that will help with the next phase of this project (https://docs.google.com/document/d/16Byq42oUSIIpDomIhy9XIyHs...). To apply, email Larry (lbabb@broadinstitute.org) with a resume.