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I have no experience with SSRIs.

I had a severe depression between 2007-2011. I used N-acetylcysteine and I benefitted a lot from it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044191/

Also consider a ketogenic diet. Currently I'm experimenting with it. So far I like it. Prepare for some extreme insomnia in the beginning. This should be getting better after a week. Should not be a problem in your case as you are already spending 22 hours in bed a day.

https://www.psychologytoday.com/us/blog/evolutionary-psychia...

https://www.psychologytoday.com/us/blog/advancing-psychiatry...


I didn't watch the youtube presentation. The subject is about depression. I got good results with acetylcysteine (NAC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044191/



https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044191/

I have benefited a lot from acetylcysteine.


Be aware of this though: https://www.science.org/content/blog-post/n-acetyl-cysteine-...

"Our results therefore support a direct role for NAC in tumor initiation."

I was going to try NAC until I read that


First of all: in mice.

Second: what are the negative impacts of alternative treatments?

Not clear what the level of impact is in humans and what the real trade-off is between better mental clarity when young/middle-aged vs. higher risk of cancer in old age. In the end we all die of something.

NAC is widely consumed, if it was a significant carcinogen you would think the effect would have been detected.


The study is at the level of cells, so 'in mice' doesn't seem inappropriate. But yes, this is one study and I'm not a medical researcher. This is merely one study I happen to know about; I'd rather mention it than not. If thinking about consuming NAC, please do your own research.


Honestly, I can't speak more highly of N-acetylcysteine. It helped me reduce my caffeine consumption to near zero and helped me battle my attention deficit issues. I bought out the entire stock of my local grocery store after trying it for a few days. I'm afraid of sounding like one of those supplement nuts but it really worked for me.


What dosage did you find effective?


The recommended dosage on the label was enough for me to see full benefits, 600mg. The effect is within an hour.

As other people in the thread said, it may not be without side effects. The FDA has not approved it as a dietary supplement. Please do your due diligence.


How did it help you to reduce caffeine consumption? And why is caffeine consumption bad?


Personally I've linked caffeine with anxiety. The more I take the more anxious I feel, particularly if I take caffeine a few days in a row. So now I'm only occasionally having some, like on weekends or on family holidays.


I tend to drink caffeine with I need to recruit mental energy. I find I don't get compulsive cravings to drink coffee and I can drink a single cup of coffee and be fine for the entire day. If anyone knows why this is, I'm all ears, I'm honestly shocked.


That’s really interesting, are you able to elaborate on dosage and how long it took to notice the effects mentioned?


Yep, me too. I started three weeks ago. It's truly unbelieveble. Here's how much satisfied I am with the results: I would gladly trade 10 years of my life to continue like this than live them as miserable as I was, plagued with rumination, anxiety and horrible attention control.

600mg, water-soluble, everyday before lunch.


I had a very nasty depression. Extreme mood swings. From very low up to neutral and back. (I never had manic episodes) Up and down, up and down... It was maddening. And extreme rumination. I discoverd acetylcysteine by accident. I didn't know it could help with depression. I felt its effects within an hour. I immediately went on the internet and searched for "acetylcysteine and depression". That is how I found above article. The internet is full of articles about the efficacy of NAC in relation to psychiatry. I used it for about 6 months. 3 * 600 mg daily.


Probably not what you are looking for, but i like these elementary books:

Mathematics for the curious - Peter Higgins

Mathematics rebooted - Lara Alcock

Mathematics: a very short introduction - Timothy Gowers

The Essence of Mathematics Through Elementary Problems

https://open.umn.edu/opentextbooks/textbooks/the-essence-of-...



plesk


You should have checked what the meaning is of this word in Dutch...


Damn. I am open to a new name...



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