It's more sarcasm than not. He's saying it was never a desirable area but tech companies moved there anyway despite theoretically having the money to be nicer places.

Name a tech company with an office in the Tenderloin.

I can't think of one, but I also can't tell the difference between the tenderloin and SOMA anymore.

Everyone's comments makes sense to me if you swap SOMA in for tenderloin

Microsoft, Twitter, Dolby are 3 who share an intersection! Square and Uber just a block away.

Zendesk, twitter, and dozens more.

Yes. It did. The mayor was in our office to celebrate the tax incentives of companies to relocate there. Then Twitter followed.