We're switching over to Zoho for our latest startup. If you have more than one Google account the switching between personal and business is a nightmare. Some features are unavailable for one or the other, and it keeps switching between the two accounts seemingly randomly. It constantly asks for a password when you want to switch back. It's more headache than it is worth to be signed in to Google.
The only issue I have with Zoho is that their calendar solution falls well behind Google's. Between the scheduling, the Android widget, and notifications, it just really doesn't feel to have the same clarity as Google's.
Could just be my experience, but I'm considering moving back to Google for my personal email just for that.