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R is not a measure of anything (i.e. real world data), it's more of a prediction based on a mathematical modeling procedure. It's not constant for a pathogen like Sars-CoV2, as it depends also on other conditions (environmental factors like temp/humidity, and social factors (norms like handshaking, etc.).

The models used to generate R-numbers have some assumptions which may or may not be valid: (1) rectangular and stationary age distribution, and (2) homogeneous mixing of the population. Thus, the result is a fairly rough estimate.

A major use is in getting a decent estimate of what percentage of a population needs to be vaccinated in order to halt the spread of a viral infection. However, this supposes 'sterilizing vaccination', i.e. vaccinated individuals are not asymptomatic carriers and spreaders of the infection. While this was the case for the smallpox vaccine, it doesn't seem to be the case with all known Covid19 vaccines, where there are many breakthrough cases (even though symptoms are reduced and hospitalization is minimal).



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