There are some dark corners where there are still differences but these are not in the "I just want to build a website"-level of complexity IME, and are more in the "I am building a large XXX,XXX lines-of-code enterprise SPA used for hours at a time for thousands of users as their primary job across varied OS and browser combinations" level of complexity. E.g. I recently had to debug how different browsers handle cookie eviction for more than 100 cookies under the same top-level domain. This is not the sort of issue you you face with a "I just want to build a website" problem.
I unknowingly relied on undefined behaviour in JavaScript Array.sort; worked fine/as expected in Firefox but then got bug reports that turned out to be Chrome/Safari.
Interesting - what were the details? I've never heard of this and rely on this feature all the time so please do share the reproduction so we can all benefit?