Re:side effects of prolonged use. Adderall is safe if used responsibly, even over the long term. We even understand how it works, which is more than you can say about eugeroics, like modafinil. Not surprising, given that it's an amphetamine and the US military handed them out like caffeine pills in WW2 and last I heard still used them sometimes. Erdos also used speed the majority of his life. I believe there's a guide to safe long-term amphetamine use on the last psychiatrist, I'd link but I'm on my phone.