Of course (pretty sure LosslessCut using ffmpeg under the covers). But this is probably one of those instances where having a GUI comes in handy. You can quickly scrub the video for the exact point you want, see where the closest I frame is (read: the place where your cut is going to start), create multiple cut segments, etc.
For simple cases where you just cut a single clip out of a longer file, I find CLI to be faster. For more complex stuff like joining several clips together or manipulating multiple files, GUI is usually the better option indeed.
