No, but there's also little we gain from trying to make it so. We know how to operate all sorts of things in Antarctica, and anything else we bring there just... needs to be operated pretty much the same way.

Finding out we can't, yet, would be pretty important.

That's the wrong approach, though. "We can't" is the default state. The thing we need to find out is how to make it so. The goal is to be able to say, after all the finding out, that yes, we can now.

Not dying just because we can't, yet, would be pretty important.

But scale does add difference as does all the complexity required to make that scale self-sustaining.