I'd expect such vacuum chambers to be relatively easy to build. The hull only has to hold one atmosphere of pressure difference, and it's pushing inward, so existing pressure tanks should be more than adequate with at most slight modifications. Generating the vacuum is mostly handling the sheer volume of air to evacuate because the quality of vacuum is irrelevant -- leaving 1% of air is as good as 0.001% of air when you are pushing doors against that pressure.

I mean in the context of actual use by humans in the day to day operation of a colony or other off-world facility.

There's obviously plenty of large vacuum chambers than can fit a door mechanism or even a small test room (the ones JPL uses to test spacecraft thermals was the first to come to mind for me, didn't know about the Plum Brook facility).