We can reasonably expect the bacteria to mutate against the new antibiotic if/once it's used. It's one shifty opponent. This may make the model obsolete, but maybe not - there'd cause to try the model. Actually, it would have been preferable to get more than one result at first...
[EDIT: Then again, would they have another candidate list? This model doesn't do toxicology. The second list was created by using existing proven-safe meds. Do they have another couple thousand materials good to go? If not, they won't be able to run a second time. ]
The EDIT is an important consideration. Like you say, the trained model doesn't do toxicology. Someone else (even some other model) must first synthesise all the candidate drugs.
We can reasonably expect the bacteria to mutate against the new antibiotic if/once it's used. It's one shifty opponent. This may make the model obsolete, but maybe not - there'd cause to try the model. Actually, it would have been preferable to get more than one result at first...
[EDIT: Then again, would they have another candidate list? This model doesn't do toxicology. The second list was created by using existing proven-safe meds. Do they have another couple thousand materials good to go? If not, they won't be able to run a second time. ]