I think the ecosystem is inching in this direction. There are already some interesting PoCs out there using Tauri (Rust based) and the deno_core Rust crate.
Do you have links to some of the more non-trivial ones?
Offtopic: Does anybody know if the WebAssembly runtime inside deno (which is actually the runtime inside v8) is exposed by any of the deno crates? A cursory search seems to indicate that it isn't. You can access it from `deno_core` through javascript, of course.
