I've got a 48" monitor, too. I also have 2 27" monitors, one one each side in portrait mode. But I'm not sure why you think multiple monitors is complex - plug them in, drag windows over to the side as needed, and go about your work.
I mean managing space on small multiple screens. The technical aspects are not complex but having to manage a small amount of screeen real estate is annoying, especially across multiple screens.
