Sequoia aims to be a "complete gnupg replacement" but in many ways it's still the same mindset as gnupg (core devs are former developers of gnupg). Sequoia also got support from VCs and just recently received significant funding from the STF which gives them resources to polish the documentation etc.
Rpgp is much smaller but also very flexible. It's easy to adjust to more specific needs. It's also associated with RustCrypto project and with Rust in general.