They can do what India and some other countries do, and legislatively ignore pharmaceutical patents when it comes to public health if drug is deemed unaffordable.
I mean, I don't think you're enforcing patent law in South Sudan regardless, but they're also just not capable of manufacturing such drugs. To get a trustworthy drug, they pretty much have to buy it from the patent-holder. India, China, and maybe Brazil are about the only exceptions. Theoretically, I guess you could say we just expect the third-world to rely on black market medicine from India, but uh, that has some risks involved.