IMO, Python should only be used for what it was intended for: as a scripting language. I tend to use it as a kind of middle ground between shell scripting and compiled languages like Rust or C. It's a truly phenomenal language for gluing together random libraries and data formats, and whenever I have some one-off task where I need to request some data from some REST API, build a mapping from the response, categorize it, write the results as JSON, then push some result to another API -- I reach for Python.

But as soon as I have any suspicion that the task is going to perform any non-trivial computation, or when I notice the structure of the program starts to grow beyond a couple of files, that's when Python no longer feels suitable to the task.