Ultra high-speed ADCs are extremely ugly to handle with microcontrollers. That's mostly FPGA territory: toggle its pins, suck the data from the ADC and offer them on a friendly parallel bus for a microcontroller (USBC->Parallel interface from FTDI).

They need a lot of pins to be toggled. Otherwise they spit out no data.

And a lot of manual stuff means it's super DMA unfriendly. And you need DMA for high-speed stuff.