There's not enough science to support either side in this debate. My guess is that a small percentage of people actually have a gluten intolerance. I also think that modern wheat can cause inflammation and gut problems. Mostly I think that reducing carbohydrates benefits anyone that isn't very active (which includes most Americans). The unfortunate truth is that the food industry is now producing more gluten-free alternatives (breads, beers, etc.), and these alternatives create a bigger insulin response than the originals.