Celiacs, for instance, seem to be a group that in previous generations succumbed to their condition, if not directly than indirectly because of general unfitness. To be honest, as a survivor of childhood lymphoma, I ought to be dead, had I been born even 25 years earlier. I question whether my genetics have enough offsetting benefits to counter that predisposition to life-threatening cancer for any of my offspring.

Advanced medical care is part of the environment in a first-world country now. I'm sure a fish would think us genetically inferior for our dependence on air to live, but we don't see it that way. A dependence on advanced medical care is ultimately no different. Assuming civilization doesn't collapse, I'd expect various dependencies on medical treatment to gradually arise in the population, but there's nothing objectively wrong with that.